Nanoscience: UNCG Graduate Research and Creativity Expo Program | April 3, 2012

The Graduate School and the Office of Research and Economic Development invite you to attend the Spring 2012 Graduate Research and Creativity Expo, to be held on April 3, 2012 in the Elliott University Center at UNCG.

Graduate Research and Creativity Expo Program

Richard D. Vestal (Nanoscience),
“Nanotechnology and Personalized Medicine: Com-bining Smart Nanomaterials with MRI-guided/High Intensity Focused Ultrasound (MRg/FUS) Surgery for the Treatment of Terminal Brain Cancer”

Cone Ballroom — 1-2pm (Poster #15)
Many people became aware of Glioblastoma (GBM), the most aggressive form of ter-minal brain cancer, when Senator Ted Kennedy was diagnosed in 2008 and quickly passed away in 2009. Patients with GBM typically only live an average of 15 months even with surgery, chemotherapy, and radiation treatments. MRg/FUS provides a way to focus ultrasound waves like sunlight through a magnifying glass destroying brain cancer cells in place without surgery. It is promising but limited by its accuracy and heating ability. Working at the atomic or “nano” scale, we have engineered a “nanovesicle” with the specific properties to overcome these limitations. Our nano-vesicle is a hollow sphere loaded with customized nanoparticles that vastly improve MRI and superheat when energized. It is designed to target brain cancer cells specifi-cally and deposit those nanoparticles inside the cancer cells. By combining smart na-nomaterials with MRg/FUS, we intend to change the outlook for GBM patients.
Faculty Mentor: Ethan Will Taylor; Christopher Kepley