Christopher Kepley, Ph.D., MBA, FAAAAI

Associate Professor, Nanoscience

Phone: 336.285.2865

Fax: 336.500.0115


Position Held:

2010-present: Consultant, Luna NanoWorks Division, Danville, VA
2009-summer: Sabbatical, University of California Los Angeles, Dept. of Clinical Immunology Allergy
2008-2010: Director, Luna Innovations, Nanoworks Division, 2006-2008
2007: Sabbatical, Harvard Medical School (summer), Boston, MA.
2002-2007: Assistant Professor, Department of Rheumatology, Immunology, and Allergy, Virginia   Commonwealth University, Richmond, VA
1999-2002: Research Assistant, Department of Pathology, Albuquerque, NM
1995-1998: Postdoctoral Fellow/Instructor, Department of Pathology, Albuquerque, NM

Research Interests

Fullerenes, Mast Cells, Cell Signaling, Atopic Dermatitis, Atherosclerosis, Wound Healing, Asthma

Selected Publications

  • Ehrich M, Van Tassell R, Li Y, Zhou Z, Kepley CL. Fullerene antioxidants decrease organophosphate-induced acetylcholinesterase inhibition in vitro. Toxicol In Vitro. 2010 Oct 1.
  • Norton SK, Dellinger A, Zhou Z, Lenk R, Macfarland D, Vonakis B, Conrad D, Kepley CL. A new class of human mast cell and peripheral blood basophil stabilizers that differentially control allergic mediator release. Clin Transl Sci. 2010 Aug;3(4):158-69.
  • Dellinger A, Zhou Z, Norton SK, Lenk R, Conrad D, Kepley CL. Uptake and distribution of fullerenes in human mast cells. Nanomedicine. 2010 Aug;6(4):575-82. Epub 2010 Feb 4.
  • Zhou Z, Lenk R, Dellinger A, MacFarland D, Kumar K, Wilson SR, Kepley CL. Fullerene nanomaterials potentiate hair growth. Nanomedicine. 2009 Jun;5(2):202-7. Epub 2009 Feb 14.
  • Ryan JJ, Bateman HR, Stover A, Gomez G, Norton SK, Zhao W, Schwartz LB, Lenk R, Kepley CL. Fullerene nanomaterials inhibit the allergic response. J Immunol. 2007 Jul 1;179(1):665-72.
  • Gomez G, Schwartz L, Kepley C. Syk deficiency in human non-releaser lung mast cells. Clin Immunol. 2007 Oct;125(1):112-5.
  • Zhao W, Kepley CL, Morel PA, Okumoto LM, Fukuoka Y, Schwartz LB. Fc gamma RIIa, not Fcgamma RIIb, is constitutively and functionally expressed on skin-derived human mast cells.


6 patent applications filed for fullerene derivative applications as nanomedicines.


See C.V.

Office Hours

By Appointment


BS in Biology, James Madison University, Harrisonburg, VA 1987
PhD in Immunology, Virginia Commonwealth University Richmond, VA 1995
MBA, College of William and Mary, 2006

Authored Papers

See C.V.