sandros prof

Marinella G. Sandros, Ph.D.

Assistant Professor, Nanoscience

Phone: 336.285.2869

Fax: 336.500.0115

Email: m_sandro@uncg.edu


Research Interests

Prof. Sandros research concentration is focused on the integration of inorganic nanomaterials and polymers with biology. She has previously designed a reagentless protein-based nanobiosensor for selective small molecules detection using conformational dependent interactions between a redox active metal complex ion RuII and the surface of a CdSe nanoparticle. Prof Sandros was able to enhance the biointerface properties of InGaP@ZnS quantum dots by encapsulating them in chitosan. Along with her collaborators, she has developed a robust and stable multifunctional siRNA delivery system and amplified Surface Plasmon Resonance Imaging (SPRi) signals using nanoparticles.

Prof. Sandros future research goals aim at:

  1. Developing novel nano-imaging probes with enhanced biointerfacing properties for deep tissue imaging.
  2. Engineering a highly integrated platform that allows for molecular diagnosis targeted drug delivery, and simultaneous monitoring and treatment of cardiovascular diseases.
  3. Introducing new methods to enhance the sensitivity of SPRi technology for medical diagnostic.

Selected Publications

  • Azari F, Sandros MG, Tabrizian M “Self-assembled Multifunctional Nanoplexes for Gene Inhibitory Therapy” submitted to ACSNano.
  • Behrendt M, Sandros MG, McKinney A, McDonald K, Tabrizian M, Maysinger D “Imaging and organelle distribution of fluorescent InGaP/ZnS nanoparticles in glial cells” Nanomedicine, 4(7), 747-61, 2009.
  • Sandros MG, Behrendt M, McKinney A, Maysinger D, Tabrizian M “Chitosan-modified InGaP/ZnS nanoparticles for live cell imaging of glia” ICCM-17 Proceedings, 2009.
  • Sandros MG, Sarraf CB, Tabrizian M “Prodrugs in Cardiovascular Therapy” Molecules, 13(5), 1156-1178, 2008.
  • Sandros MG, Behrendt M, Maysinger D, Tabrizian M “InGaP@ZnS-Enriched Chitosan Nanoparticles: A Versatile Fluorescent Probe for Deep Tissue Imaging” Advanced Functional Materials 17(18), 3724-3730, 2007.
  • Sandros MG, Tabrizian M “Drug-Eluting Stents Devices: Clinical Relevance and Perspective” New Technologies in Vascular Biomaterials, Fundamentals about Stents II , ESVB, EURPROT: Strasbourg, France 15, 147-160, 2007.
  • Aryal BP, Neupane KP, Sandros MG, Benson DE “Metallothioneins initiate semiconducting nanoparticle cellular toxicity” Small 2(10), 1159-63, 2006.
  • Sandros MG, Shete V, Benson DE “Selective, Reversible, Reagentless Maltose Biosensing with Core-Shell Semiconducting Nanoparticles" The Analyst, 131, 229, 2006.
  • Sandros MG, Gao D, Benson DE “A Modular Nanoparticle-Based System for Reagentless Small Molecule Biosensing” J. Am. Chem. Soc., 127 (35), 12198 -12199, 2005.
  • Sandros MG, Gao D, Gokdemir C, Benson DE “General, high-affinity approach for the synthesis of fluorophore appended protein nanoparticle assemblies” Chem. Commun. (22), 2832 – 2834, 2005.

See more (CV)...

Patents

Sandros MG, Tabrizian M. A new class of NIR quantum dots. Patent ROI : 08016 (Under consideration), 2007

Grants

$40,000 Friends for an Earlier Breast Cancer Test - Earlier.org

Office Hours

By Appointment

Education

Post-Doctoral Studies, Biomedical Engineering

McGill University, 2006-2010

Ph.D., Bioinorganic Chemistry

Wayne State University, 2006

B.Sc., Honors Chemistry, Minor in German Studies

University of Windsor, 2001